Optimal Ship Maintenance Scheduling Under Restricted Conditions and Constrained Resources

The research presented in this dissertation addresses the application of evolution algorithms, i.e. Genetic Algorithm (GA) and Differential Evolution algorithm (DE) to scheduling problems in the presence of restricted conditions and resource limitations. This research is motivated by the scheduling of engineering design tasks in shop scheduling problems and ship maintenance scheduling problems to minimize total completion time. The thesis consists of two major parts; the first corresponds to the first appended paper and deals with the computational complexity of mixed shop scheduling problems. A modified Genetic algorithm is proposed to solve the problem. Computational experiments, conducted to evaluate its performance against known optimal solutions for different sized problems, show its superiority in computation time and the high applicability in practical mixed shop scheduling problems. The second part considers the major theme in the second appended paper and is related to the ship maintenance scheduling problem and the extended research on the multi-mode resource-constrained ship scheduling problem. A heuristic Differential Evolution is developed and applied to solve these problems. A mathematical optimization model is also formulated for the multi-mode resource-constrained ship scheduling problem. Through the computed results, DE proves its effectiveness and efficiency in addressing both single and multi-objective ship maintenance scheduling problem

YOUTH EDUCATION AND ORIENTATION TOWARD HO CHI MINH'S IDEOLOGY IN THE CONTEMPORARY CONTEXT

During his time, Former President Ho Chi Minh had consistently emphasized the central role, position, and competence of the young generation in realizing the Party and the people's revolutionary path. He believed, “The youth are the future owners of the home country. Indeed, the vitality of the home country, whether it is prosperous or wilting, depends largely on the youth.” Before passing, his words had become the guiding principle for leaders of the Communist Party of Vietnam, “Nurturing future revolutionary generations is of utmost importance and necessity.” Especially, given that the functioning of the current market economy has revealed its multiple drawbacks, it is salient to educate and orient the youth following Ho Chi Minh's ideology to produce a young generation that is moral in ethics and efficient in labour.  Article visualizations

ANTIBACTERIAL AND PHOTOCATALYTIC ABILITY OF THE Ag/TiO2 COATING ON THE GLASS SURFACE.

The coating on the glass surface was made by heating the mixture of resinate Ag and tetra-n-butyl orthotitanate (TBO) at 570 oC for 1 hour. The characteristics and structure of the mixture Ag/TiO2 with the content of Ag : TiO2 from 0 – 8 (% mol) were studied by the methods such as XRD, FTIR, UV-viz, SEM, EDS. The research results of antibacterial ability and the degradation of blue methylene (MB) were shown that this coating can be used for antibacterial and photocatalytic abilit

Proton Induced X-Ray Emission (PIXE) Analysis on Thick Samples at HUS 5SDH-2 Tandem Accelerator System

The main purpose of this work is to establish a method of elemental analysis by Proton-Induced X-ray Emission (PIXE) technique on thick samples. Our study has been carried out at Hanoi University of Science (HUS) using a 5SDH-2 Tandem accelerator. The X-ray spectra were measured by a Si(Li) detector (FWHM = 139 eV at 5.9 keV) and analyzed off-line using GUPIX software. The validity of the proposed method has been checked through its application to NIST standard samples. The concentrations of the elements have been determined in the standard samples are in agreement with the certified values within the error limits. Our method is now used for the analysis of environmental samples at our laborator

ARSENIC POLLUTION IN TUBE WELL WATER AT HANOI SUBURB VILLAGES

Joint Research on Environmental Science and Technology for the Eart

ARSENIC POLLUTION IN GROUNDWATER IN RED RIVER DELTA, VIETNAM : SITUATION AND HUMAN EXPOSURE

Joint Research on Environmental Science and Technology for the Eart

Genomic serotyping, clinical manifestations, and antimicrobial resistance of non-typhoidal Salmonella gastroenteritis in hospitalized children in Ho Chi Minh City, Vietnam

Nontyphoidal Salmonella (NTS) are among the most common etiological agents of diarrheal diseases worldwide and have become the most commonly detected bacterial pathogen in children hospitalized with diarrhea in Vietnam. Aiming to better understand the epidemiology, serovar distribution, antimicrobial resistance (AMR), and clinical manifestation of NTS gastroenteritis in Vietnam, we conducted a clinical genomics investigation of NTS isolated from diarrheal children admitted to one of three tertiary hospitals in Ho Chi Minh City. Between May 2014 and April 2016, 3,166 children hospitalized with dysentery were recruited into the study; 478 (∼15%) children were found to be infected with NTS by stool culture. Molecular serotyping of the 450 generated genomes identified a diverse collection of serogroups (B, C1, C2 to C3, D1, E1, G, I, K, N, O, and Q); however, Salmonella enterica serovar Typhimurium was the most predominant serovar, accounting for 41.8% (188/450) of NTS isolates. We observed a high prevalence of AMR to first-line treatments recommended by WHO, and more than half (53.8%; 242/450) of NTS isolates were multidrug resistant (MDR; resistant to ≥3 antimicrobial classes). AMR gene detection positively correlated with phenotypic AMR testing, and resistance to empirical antimicrobials was associated with a significantly longer hospitalization (0.91 days; P = 0.04). Our work shows that genome sequencing is a powerful epidemiological tool to characterize the serovar diversity and AMR profiles in NTS. We propose a revaluation of empirical antimicrobials for dysenteric diarrhea and endorse the use of whole-genome sequencing for sustained surveillance of NTS internationally

The transfer and decay of maternal antibody against Shigella sonnei in a longitudinal cohort of Vietnamese infants.

BACKGROUND: Shigella sonnei is an emergent and major diarrheal pathogen for which there is currently no vaccine. We aimed to quantify duration of maternal antibody against S. sonnei and investigate transplacental IgG transfer in a birth cohort in southern Vietnam. METHODS AND RESULTS: Over 500-paired maternal/infant plasma samples were evaluated for presence of anti-S. sonnei-O IgG and IgM. Longitudinal plasma samples allowed for the estimation of the median half-life of maternal anti-S. sonnei-O IgG, which was 43 days (95% confidence interval: 41-45 days). Additionally, half of infants lacked a detectable titer by 19 weeks of age. Lower cord titers were associated with greater increases in S. sonnei IgG over the first year of life, and the incidence of S. sonnei seroconversion was estimated to be 4/100 infant years. Maternal IgG titer, the ratio of antibody transfer, the season of birth and gestational age were significantly associated with cord titer. CONCLUSIONS: Maternal anti-S. sonnei-O IgG is efficiently transferred across the placenta and anti-S. sonnei-O maternal IgG declines rapidly after birth and is undetectable after 5 months in the majority of children. Preterm neonates and children born to mothers with low IgG titers have lower cord titers and therefore may be at greater risk of seroconversion in infancy

Antibiotic use and prescription and its effects on Enterobacteriaceae in the gut in children with mild respiratory infections in Ho Chi Minh City, Vietnam. A prospective observational outpatient study.

BACKGROUND AND OBJECTIVES: Treatment guidelines do not recommend antibiotic use for acute respiratory infections (ARI), except for streptococcal pharyngitis/tonsillitis and pneumonia. However, antibiotics are prescribed frequently for children with ARI, often in absence of evidence for bacterial infection. The objectives of this study were 1) to assess the appropriateness of antibiotic prescriptions for mild ARI in paediatric outpatients in relation to available guidelines and detected pathogens, 2) to assess antibiotic use on presentation using questionnaires and detection in urine 3) to assess the carriage rates and proportions of resistant intestinal Enterobacteriaceae before, during and after consultation. MATERIALS AND METHODS: Patients were prospectively enrolled in Children's Hospital 1, Ho Chi Minh City, Vietnam and diagnoses, prescribed therapy and outcome were recorded on first visit and on follow-up after 7 days. Respiratory bacterial and viral pathogens were detected using molecular assays. Antibiotic use before presentation was assessed using questionnaires and urine HPLC. The impact of antibiotic usage on intestinal Enterobacteriaceae was assessed with semi-quantitative culture on agar with and without antibiotics on presentation and after 7 and 28 days. RESULTS: A total of 563 patients were enrolled between February 2009 and February 2010. Antibiotics were prescribed for all except 2 of 563 patients. The majority were 2nd and 3rd generation oral cephalosporins and amoxicillin with or without clavulanic acid. Respiratory viruses were detected in respiratory specimens of 72.5% of patients. Antibiotic use was considered inappropriate in 90.1% and 67.5%, based on guidelines and detected pathogens, respectively. On presentation parents reported antibiotic use for 22% of patients, 41% of parents did not know and 37% denied antibiotic use. Among these three groups, six commonly used antibiotics were detected with HPLC in patients' urine in 49%, 40% and 14%, respectively. Temporary selection of 3rd generation cephalosporin resistant intestinal Enterobacteriaceae during antibiotic use was observed, with co-selection of resistance to aminoglycosides and fluoroquinolones. CONCLUSIONS: We report overuse and overprescription of antibiotics for uncomplicated ARI with selection of resistant intestinal Enterobacteriaceae, posing a risk for community transmission and persistence in a setting of a highly granular healthcare system and unrestricted access to antibiotics through private pharmacies. REGISTRATION: This study was registered at the International Standard Randomised Controlled Trials Number registry under number ISRCTN32862422: http://www.isrctn.com/ISRCTN32862422